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The simplest screening test is a single question: Are you depressed? 2004 Jun. 35(6):1383-90. The researchers found that adolescents with major depressive disorder may have regional blood flow deficits in the left anterofrontal and left temporal cortical regions, with greater right-left perfusion asymmetry than healthy control patients. A variety of laboratory tests and bloodwork may be needed to determine the correct eating disorder diagnosis and assess the appropriate level of care for an affected individual. Nezu AM. [Medline]. 72(5):598-604. Evidence-based psychosocial treatments for child and adolescent depression. Kaplan and Saddock’s Comprehensive Textbook of Psychiatry 8th edition. [Medline]. Copeland JR, Beekman AT, Dewey ME, Hooijer C, Jordan A, Lawlor BA, et al. J Am Acad Child Adolesc Psychiatry. 78(5):804-14. 2004 May. J Consult Clin Psychol. 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Am J Psychiatry. Abkevich V, Camp NJ, Hensel CH, Neff CD, Russell DL, et al. There are many conditions, identifiable by lab investigations, that can cause a host of cognitive, emotional, or behavioural changes. Nezu, A. M. Problem solving and behavior therapy revisited. Cooper C, Katona C, Lyketsos K, et al. Solving life’s problems: A 5-step guide to enhanced well-being. Because they are physicians, psychiatrists can order or perform a full range of medical laboratory and psychological tests which, combined with discussions with patients, help provide a picture of a patient's physical and mental state. 2001 Apr. [Medline]. Available at http://www.medscape.com/viewarticle/820313. Genome Med. [Medline]. 2004 Aug 18. 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Ann Intern Med. Rush AJ, Trivedi MH, Wisniewski SR, Nierenberg AA, Stewart JW, Warden D, et al. Liver disease which results in lowered plasma protein can cause some drugs to be less protein bound which increases their level of activity including both intended effects and side effects. David Bienenfeld, MD is a member of the following medical societies: American Medical Association, American Psychiatric Association, Association for Academic PsychiatryDisclosure: Nothing to disclose. Ishak WW, Ha K, Kapitanski N, Bagot K, Fathy H, Swanson B, et al. 2012 Oct. 28(10):1717-24. [Medline]. Leon AC, Solomon DA, Li C, et al. Point-of-care references for mental health professionals. JAMA. 68(6):843-53. Schwarz E, Izmailov R, Spain M, et al. 2008 Apr. To determine a diagnosis and check for related complications, you may have: 1. J Am Acad Child Adolesc Psychiatry. The effect of exercise in clinically depressed adults: systematic review and meta-analysis of randomized controlled trials. 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